Bioengineered post-natal recombinant tooth bud models

Whole Tooth Regeneration Using a Bioengineered Tooth

Ante-natal and Post-natal Care

glucose thlirapy is call(ed forIt' rar l ese \IIIvt'lee these measures fail, abortioni hias to he iln(luce(l. Ana.stlhsia is e1-r (lamngerous in these cases. (Gas and oxygen sihouldl be chloseln. Results of Treabtne ii t .-Ou)t of 790 patientIs admitted to III \ wards at the Ri)va Maternity HIospital from ulgust, 1988, till tI e end of 198-, tliirteen] cases were admitte(d as hlypercmesis. Of t...

Transcription factor Sp3 is essential for post-natal survival and late tooth development.

Sp3 is a ubiquitously expressed transcription factor closely related to Sp1 (specificity protein 1). We have disrupted the mouse Sp3 gene by homologous recombination. Sp3-deficient embryos are growth retarded and invariably die at birth of respiratory failure. The cause for the observed breathing defect remains obscure since only minor morphological alterations were observed in the lung, and su...

Promoting bioengineered tooth innervation using nanostructured and hybrid scaffolds.

The innervation of teeth mediated by axons originating from the trigeminal ganglia is essential for their function and protection. Immunosuppressive therapy using Cyclosporine A (CsA) was found to accelerate the innervation of transplanted tissues and particularly that of bioengineered teeth. To avoid the CsA side effects, we report in this study the preparation of CsA loaded poly(lactic-co-gly...

Fully functional bioengineered tooth replacement as an organ replacement therapy.

Current approaches to the development of regenerative therapies have been influenced by our understanding of embryonic development, stem cell biology, and tissue engineering technology. The ultimate goal of regenerative therapy is to develop fully functioning bioengineered organs which work in cooperation with surrounding tissues to replace organs that were lost or damaged as a result of diseas...